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Courses

The doctoral courses are divided into two levels: those numbered 70000 are fundamental core courses and those numbered 80000 are advanced, special topics courses and seminars. Typically students complete the core courses and two semesters of seminar during their first year (30 credits of graduate courses).

Unless otherwise stated, all courses are 45 hours, 3 credits.


Biochemistry Program Core Courses


(Required of all students, except fro BICM 71130).

BICM 71010 - Advanced Biochemistry I (Enzymology/Metabolism)
Protein structure, enzymology, and immunology; metabolism of carbohydrates, lipids, amino acids, and nucleotides; regulation of these processes.
Prerequisite: A one semester course in biochemistry

BICM 71020 - Advanced Biochemistry II (Bioenergetics/Molecular Biology)
Membranes: structure, transport and other functions; muscle and cytoskeletal biochemistry; bioenergetics: respiration and photosynthesis; nucleic acids and protein synthesis.
Prerequisite: A one semester course in biochemistry

BICM 71110 - Research Techniques in Biochemistry I
2-6 credits
During the course of one year each student will work in 3 or 4 research laboratories to solve clearly defined biochemical problems by use of modern research techniques.
Corequisite: BICM 71010

BICM 71120 - Research Techniques in Biochemistry II 
2-6 credits
Continuation of Biochemistry 71110
Prerequisite: BICM 71110

BICM 71130 - Research in Biochemistry
2-6 credits
One biochemistry problem will be solved by use of modern research techniques.
Prerequisites: BICM 71110 and BICM 71120

BICM 72010 - Basic Seminar in Biochemistry I
1 credit
Each student will present at least one published paper related to the topics covered in BICM 71010

BICM 72020 - Basic Seminar in Biochemistry II
1 credit
Each student will present at least one published paper related to the topics covered in BICM 71020

BICM 75000 - Bioorganic Chemistry
Chemistry of amino acids, sulfur and phosphates; proton transfer; catalysis by fields, hydronium and hydroxide ions; general acid-base catalysis; nucleophilic and electrophilic catalysis; metal ion catalysis; intramolecular catalysis; multiple catalysis; catalysis by complexation.

BICM 77000 – Physical Biochemistry
Principles and applications of classical and statistical thermodynamics, spectroscopy, kinetics and x-ray crystallography to the study of biomacromolecular and biochemical systems.

Advanced Courses


BICM 81000 – Seminar in Biochemistry

15 hours, 1 credit
Three semesters required of all students

BICM 82000 – Doctoral Disseratation Research
Credits variable
Prerequisite: The First Level Examination

BICM 83000 – Biochemistry of Lipids and Membranes
Purification and physical characterization of lipids and membrane proteins; bilayer properties, lipid dynamics, transport proteins and energy; cytoskeletal membrane proteins; receptors; membrane-bound enzymes; signal in cells; and membrane biogenesis.

BICM 84000 - Enzymology
Purification of enzymes; kinetic and structural properties; mechanism of action; studies of active sites; regulation of catalytic activity.

BICM 85000 - Nucleic Acid Metabolism and Function
Current views on the molecular structure of DNA and RNA, their biosynthesis and degradation, their functional role in protein synthesis and in development.

BICM 86000 – Metabolic Pathways and their Control Mechanisms
The major metabolic pathways in plants, animals and microorganisms; multienzyme systems and some mathematical models applicable to them; mechanisms of regulation such as enzymic induction and feedback inhibition.

BICM 87000 - Bioinformatics
The use of bioinformatic methods to study the properties of biological macromolecules, including proteins, carbohydrates, lipids, cofactors, and nucleic acids. Concentration on visualization and evolutionary and homology relationships among macromolecular sequences and structures.

BICM 88800 – Current Topics in Biochemistry
15 hours, 1 credit
Recent advances in selected areas of biochemistry will be presented.

BICM 88900 – Special Topics in Biochemistry
Lectures dealing with specialized topics or recent advances in the field.

BICM 90000 – Dissertation Supervision
1 credit
Required of all students
Prerequisite: Completion of all required courses.