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Displaying results 51-100 (of 123)
RNA metabolism during aging and the relationship between cell death (apoptosis) and aging
Ikui, Amy E.
molecular targets of Cyclin-Cdk, and the biological importance of the new cyclin targets in S. cerevisiae.
computational biochemistry; heavy metal poisoning.
DNA replication, DNA repair, ABC and AAA ATPases, Macromolecular complexes, X-ray crustallography.
Nutritional biochemistry, One carbon metabolism, Nutrigenetics and Nutrigenomics, Maternal and child health
Bioinorganic chemistry, metal enzymes, and drug delivery.
protein aggregation; drug development for pathological protein aggregation diseases; protein aggregation at metal surfaces.
natural products chemistry and chemical proteomics.
Kennelly, Edward J.
biologically active phytochemicals from medicinal plants.
virus-host interaction; macromolecular machines; structural biology.
the molecular basis of the transcription-coupled repair process and how these interactions regulate gene expression after DNA damage.
forensic sciences: DNA fingerprinting, short tandem repeat analysis, forensic serology.
creating new enzyme-based cancer therapies and protein based biological solar energy devices – ‘green’ solar panels.
design, synthesis and evaluation of tight-binding inhibitors of clinically important enzyme targets using a combination of rational and combinatorial approaches, enzyme kinetics and molecular modeling.
understanding the role of water in molecular recognition.
computational biophysics; protein folding and stability, molecular recognition, protein-membrane interactions.
the function and regulation of a class of neuropeptide neurotransmitters in the genetic model organism
role of amyloids in cell adhesion, interactions of fungal pathogens with host, yeast cell surface structure and biogenesis.
telomere function in human cells.
molecular self-assembly, coarse-grained molecular dynamics, polymer-drug and polymer-membrane interactions.
spectroscopy and reaction mechanisms of heme enzymes; radicals in biological systems.
combinatorial chemistry, molecular recognition, protein-ligand interactions, functional bio-nano materials.
biology of glutamate
bio-nanotechnology, protein nanotubes, electronics, sensors.
the role of RNA-binding proteins during development of Drosophila melanogaster, with a focus on oogenesis and the adult nervous system.
developmental genetics and autophagy in C. elegans.
Molecular genetics, regulation of gene expression, yeast genetics.
peptide transport; yeast mating pheromones; prenylated peptides synthesis; peptide hormones and signal transduction; design of antimicrobial agents
study of fluorescent sensors, biodegradable hydrogels for biomedical applications and CO2 sequestration and reduction.
chromatin, transcription and immune system development
boronic acids as enzyme inhibitors and enzyme analogs; combinatorial approaches to enzyme inhibition.
understanding of selected membrane proteins and their function on an atomic level of structural detail.
biosynthesis of mycobacterial iron-chelating compounds utilized for iron uptake (siderophores); elucidate the biosynthesis of lipidic mycobacterial virulence factors called DIMs; and develop compounds with utility as leads for drug development or chemical biology tools.
bionanotechnology, synthetic polymer chemistry, biopharmaceutical chemistry and targeted drug delivery
primate innate immunity; host pathogen interactions; parasites.
Stem cells, tissue engineering, and nanotechnology
signal transduction pathways
Rotenberg, Susan A.
structure-function of protein kinase C and its role in cancer cell metastasis.
Expression of Ribosomal and Transfer RNA Genes/Cooperative Colonial Patterning in the Genus Bacillus.
Tetrapyrroles: Heme & Siroheme Biosynthesis in E. coli; Lipid-mediated Hemagglutination.
bioorganic studies of olfactory molecular recognition; mammalian pre-mRNA 3' end processing regulation by protein phosphorylation; and development of new methods to deliver miRNA and siRNA to human cells.
DNA repair, mutation and recombination in yeast.
interplay between transcription factors and their co-regulators (genetic factors) and the chromatin alterations they catalyze (epigenetic processes) in orchestrating gene expression patterns that in turn program the fate and function of hematopoietic stem and progenitor cells.
combining spectroscopy, specifically, resonance Raman and surface enhanced Raman spectroscopy, sol-gel encapsulation of proteins and nanoparticles.
Whole plant mineral nutrition and homeostasis, interaction of metal contaminants such as Cd with mineral nutrients in terms of ion transport, and the transfer of these minerals through the food chain.
Displaying results 51-100 (of 123)