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Brian R. Gibney
Position: Associate Professor
Campus Affiliation: Brooklyn College
Phone: (718)951-5000 x6636
Room Number: 254 NE
Degrees/Diplomas: Ph.D., University of Michigan
Research Interests: Inorganic, Molecular Biophysics, Biochemistry

Areas of Expertise:

While DNA is the blueprint for the cell, it is the proteins that do the bulk of the work. About 30% of proteins require metal ions for proper function and their dysfunction leads to human disease. The Gibney Lab takes a constructive approach toward understanding metalloprotein structure-function relationships. Using inorganic chemistry and protein biophysics, his lab designs and synthesizes simplified metalloproteins (maquettes) to test the fundamental tenets of metalloprotein engineering.

Selected Publications:

"Heme" entry in Encyclopedia of Biophysics, Gordon Roberts, Ed., Springer. (Books and Publications: Other Article) 2013

"Metallopeptides as Tools to Understand Metalloprotein Folding and Stability." Protein Folding and Metal Ions -- Mechanisms, Biology and Disease. Eds. C.M. Gomes and P. Wittung-Stafshede. New York: CRC Press. 227-45. (Books and Publications: Chapter) 2011

Deng, B., S. Parthasarathy, W. Wang, B.R. Gibney, K.P. Battaile, S. Lovell, D.R. Benson and H. Zhu. "Unique Heme Pocket in Human Ncb5or and Structural Basis for Intra-Domain Electron Transfer., Journal of Biological Chemistry 285: 30181-91. (Books and Publications: Peer Reviewed Article) 2010

Reedy, C.J., M.M. Elvekrog and B.R. Gibney. "Development and Analysis of a Heme Protein Structure-Electrochemical Function Database." Nucleic Acids Research 36: D307-13. (Books and Publications: Peer Reviewed Article) 2008