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Displaying results 1-50 (of 123)
role of apolipoprotein D in the development of atherosclerosis via oxidative stress signaling pathways and the modulation of HDL cholesterol.
I am investigating the role of apolipoproteins in the development of atherosclerosis via oxidative stress signaling pathways and the modulation of HDL cholesterol. In addition, other research projects will determine the role of apolipoproteins in the context of obesity and cancer.
Alonso, Alejandra del Carmen
unravelling the mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies.
molecular mechanisms of drug-induced toxicity and cell death in the brain.
functional characterization of transcriptional multipotency and gene regulatory networks during development.
neurobiology and neurochemistry.
the role of p53 in tumorigenesis.
biophotonics; mRNA structure; 4D visualization of mRNA transport using molecular beacons; gene expression regulation via miRNAs and piRNAs.
Leveraging nanotechnology and organic chemistry to address the role of carbohydrates in disease and development
the signal transduction of cell density sensing.
structure and dynamics of cell signaling proteins; cancer research; biochemistry; biophysics; structural biology.
expression of alpha-galactosidase A using a baculovirus vector-ilvGMEDA gene cluster transcripts in Escherichia coli K-12.
Epigenome-wide studies of cell identity in normal brain development and during glioma formation/gene-environment interaction in neural tissue/population neuroscience/myelination
Chang, Emmanuel J.
biological applications of mass spectrometry, including analysis and methods development for protein phosphorylation and other post-translational modifications
molecular mechanism of protein structure and dynamic changes in mediating bacterial host sensing.
the roles environmental toxins (dithiocarbamate compounds) play in neurodegenerative diseases, such as Parkinson’s disease
My research interest spans across nanotechnology and nanomedicine with the design of theranostic nanoparticle systems specifically for concurrent imaging and therapy of disease
conformation, dynamics and interactions of complex biomolecules; G-quadruplexed DNA; surfactants and model membrane systems; fluorescence spectroscopy.
des Georges, Amedee
The mechanisms of cell regulation at the molecular level. Cyro-electron microscopy as a main structural biology tools is used since it is extremely powerful at looking at very large macromolecular complexes and at looking at different states of function and different ligands
physical biochemistry/enzymology, protein-small molecule interaction, and Raman and IR spectroscopy.
the effect of Pb2+ and Mg2+ on bone mineral properties and on the bone protein osteocalcin. NMR structural and functional studies of the gap junction protein Connexin 32.
Drain, Charles Michael
photodynamic therapeutics, biosensors, antibacterial agents, self-assembly
protein and RNA granules, intracellular liquid organelles, and protein assembly and aggregation, as well as neurophysiology and degeneration
Cell-type specific transcription in neural development
design and synthesis of ionic dendrimers.
Fata, Jimmie E.
molecular mechanisms underlying mammary gland development and breast cancer.
cell polarity, golgi membrane trafficking, cytoskeletal motors.
Using targeted mutagenesis and mouse genetics to study how the brain functions
the ubiquitin pathway and neurodegeneration.
Signal transduction in excitable tissues, G. proteins, MAPKinase pathways
Thermodynamics of macro-molecular binding, protein conformational equilibria and allostery and molecular modeling and high performance computing.
Structural studies of environmental sensor proteins, aiming to gain insight into natural regulation and understand how to apply these principles for artificial control
Chemical biology, organic chemistry, biochemistry, molecular biology, cell biology, cancer, HIV and neurodegenerative disorders
protein-protein interactions in space and time.
metalloprotein design, artificial photosynthesis, heme proteins, metal induced protein folding, zinc finger proteins.
fibroblast growth factor homologous factors.
protein-nucleic acid interactions and biological regulation.
packaging, replication and transcription of cystoviridae.
understanding mechanisms underlying hematopoietic cancer/inflammation using Drosophila molecular genetics.
innate mechanisms of defense against bacterial pathogens.
Greenbaum, Nancy L.
bioinorganic chemistry; molecular biology; physical biochemistry/biophysical chemistry; structural biology.
theoretical analysis of intra-protein electron and proton transfers in mitochondrial and photosynthetic proteins.
Biophysical and bioorganic chemistry, spectroscopy, quantum chemical calculations
Proton Leakage in Biomembranes, Why We Make Cholesterol, Cardiolipin and Polyunsaturated Fatty Acids, Lipid Design and ATP Synthesis and Consumption.
synthesis and evaluation of central nervous system receptor ligands and psychoactive natural products.
Henderson, Ann S.
Genetics, Cell Regulation and Environmental Hazards
reconstructing the evolutionary history of venomous marine snails, and investigating their toxins as biochemical tools for characterizing cellular communication in the nervous system and as potential drugs.
Displaying results 1-50 (of 123)